Scientists find 21 EXISTING drugs that are effective against COVID-19
The exploration of the drugs was titled ‘Discovery of SARS-COV-2 antiviral drugs through large-scale compound repurposing’.
A group of scientists from around the world has successfully identified 21 known drugs to be effective against SARS-COV-2, the Coronavirus which causes the Covid-19 infection. These drugs can be administered as a preventive measure, at the initial stage and the later stages of the virus.
The exploration of the drugs was titled ‘Discovery of SARS-COV-2 antiviral drugs through large-scale compound repurposing’. Under this study, researchers analyzed one of the world’s largest collection of existing drugs for their efficacy in stopping the replication of SARS-COV-2.
Initially, through laboratory tests, it was observed that 100 current drugs contained different levels of antiviral concentrations. As the testing developed further, 21 drugs were declared safe for humans to treat Covid-19. Four medications from the group of 21 were found to improve the activity of Remdesivir, a current standard-of-care treatment for Covid-19.
Regarding this, Sumit Chanda, a leader of the research group and professor at Sanford Burnham Prebys Medical Discovery Institute, said:
Remdesivir has proven to reduce the recovery time of Covid-19 infection, but it does not work equally for every Coronavirus patient. However, my research team has identified existing and readily available drugs that can improve the medical activity of Remdesivir.
Here is a breakdown of the 21 drugs that can effectively stop SARS-COV-2 from replication:
- Thirteen drugs have previously been evaluated during clinical trials and are safe and effective for COVID-19 patients.
- Three drugs have already been approved by the Food and Drug Administration (FDA), including Remdesivir.
- Four drugs have shown to increase the effectiveness of Remdesivir.
Of all the 21 drugs, Clofazimine, Hanfangchin A, Apilimod, and ONO 5334 are recognized as the best alternatives of Coronavirus vaccine for effective treatment of Covid-19.
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